Clinical Research Center

The MIT Clinical Research Center (CRC), partially funded by Harvard Catalyst | The Harvard Clinical and Translational Science Center, offers MIT scientists and engineers the tools and technologies to conduct clinical studies in humans. Our clinical services (listed in the table below) promote the translation of basic science and engineering advances into patient-oriented research, and ultimately into clinical practice.

To facilitate collaboration among researchers at multiple institutions, over 20 institutions, including MIT, have signed on to Harvard Catalyst’s Master IRB Reliance Agreement which facilitates review of multi-site human studies. The process is initiated here: IRB Cede Review Form.

The MIT CRC was first established in 1964 to provide clinical services that would support the application of basic science and engineering to the study of human physiology and the development of treatments for human diseases. This vision has since expanded to reflect the parent mission of MIT”s Institute of Medical Engineering (IMES), which aims to accelerate innovation by discovering, designing, and delivering new medical devices and products.

Services Available

Protocol Consultation

  • Study Design
  • Budget Planning
  • Protocol Review
  • COUHES Navigation
  • Regulatory Assistance
  • Study Coordination
  • Subject Recruitment

 

Clinical Services

  • Informed Consent Process
  • Subject Eligibility
  • History and Physical Exam
  • Subject Monitoring
  • Data Collection
  • Phlebotomy / Biopsy
  • Radiology Services
  • Pathology Services (Human / Animal)
  • Subspecialty Consultation

 

Ancillaries

  • Pharmacy Access
  • Basic to Complex Laboratory Testing
  • Tissue Specimens
  • Database Management
  • Animal to Human Management
  • Model to Animal Management
  • Biostatistics
  • Computational Modeling

 

Clinical Testing Space

  • Waiting room
  • Two clinical testing rooms
  • Wet Lab processing facility
  • Two clinical beds
  • Infusion / phlebotomy station
  • -80 C specimen storage freezer
  • Computational Facilities

 

Physiology Testing Laboratory

  • Tilt Table (hemodynamic monitoring)
  • Treadmill
  • Bioelectrical Impedance Monitoring
  • Blood pressure monitoring
  • Oxygen Monitoring
  • Glucose Monitoring
  • Anthropometrics
    – ECG
    – Peak flow monitoring
    – Extensive access to other tests per protocol

 

Neurocognitive / Behavioral Testing Lab

  • Two testing rooms with audio/video monitoring
  • Observation Room

 

To learn more about the services available, please contact us at 617-253-6337 or clinicalresearch@mit.edu.